Eficácia de anti-helmínticos em estrongilídeos de equídeos na região semiárida de Minas Gerais

Abstract

The cyathostomins are today the mainly nematodes in equines. The indiscriminated uses of drugs in attempt to control these parasites can acelerate the anthelmintic resistance appearance. The aim of this work was to analyse the anthelmintic efficacy of closantel, fenbendazole, invermectin and abamectin anthelmintics in equines naturally infected on the region of semiarid in the state of Minas Gerais. The FEC has been realized on -3, 0 and 14 days in 752 equines. On 0 day, the animals was submited to the following treatments in an oral form, takking into account the healty weight: Closantel oral solution (20 mg/kg), paste containing fenbendazole (7.5 mg/kg), paste containing invermectin (200 mcg/kg), and paste containing abamectin (200 mcg/kg). The faecal egg count reduction test (FECRT) was realized in 569 equines. The datas has been analysed with “eggCounts 2.3” package, on RStudio software using Bayesian model with paired design. The treatment with Closantel shows confirmed anthelmintic resistance on 100% of yards analysed, while the treatment with fenbendazole shows 58.5% of proper efficacy. Invermectin and abamectin obtained a proper efficacy of 77.3% and 69.6% on yards analysed. The results found out on this study highlight the strongylides resistance to all drugs administrated. The control of this paraistes only with these drugs shows to be flawed, being necessary to establish an integrated paraiste control in a way that the efficacy of anthelmintic available commercially bhe preserved and parasite resistance will be retarded.